Ciprobel

every 5 ml contains:

• Ciprofloxacin hydrochloride BP eq. ciprofloxacin 125 mg

Ciprobel 125 mg/5 ml suspension is indicated for the treatment of the following infections. Particular attention should be paid to available information on resistance to ciprofloxacin before starting therapy.
Official guidance on the proper use of antibacterial agents should be used.

Adults

• Lower respiratory tract infections caused by gram-negative bacteria (exacerbation of chronic obstructive pulmonary disease, bronchopulmonary infections in cystic fibrosis or bronchiectasis, pneumonia);
• Chronic purulent otitis;
• Exacerbation of chronic sinusitis, especially if it is caused by gram-negative bacteria;
• Urinary tract infections;
• Infections of the genital organs (gonococcal urethritis and cervicitis caused by susceptible Neisseria gonorrhoeae;
• epididymo-orchitis, including cases caused by susceptible Neisseria gonorrhoeae; pelvic inflammatory diseases, including cases caused by susceptible Neisseria gonorrhoeae);
• Gastrointestinal tract infections (eg, traveler’s diarrhea);
• Intra-abdominal infections;
• Skin and soft tissue infections caused by gram-negative bacteria;
• Malignant otitis externa;
• Bone and joint infections;
• Prevention of invasive infections caused by Neisseria meningitidis;
• Inhalational anthrax (post-exposure prophylaxis and treatment).

Ciprofloxacin may be used in the treatment of neutropenic patients with fever thought to be due to a bacterial infection.

Children and teenagers

• Bronchopulmonary infections in cystic fibrosis caused by Pseudomonas aeruginosa;
• Complex urinary tract infections and pyelonephritis;
• Inhalational anthrax (post-exposure prophylaxis and treatment).

Ciprofloxacin may also be used to treat severe infections in children and adolescents when deemed necessary.
Treatment should only be prescribed by doctors experienced in treating cystic fibrosis and/or severe infections in children and adolescents.

Ciprobel is prescribed for adults orally for uncomplicated urinary tract infections 0.125-0.5 g 2 times a day, for complicated urinary tract infections and respiratory tract infections – 0.25-0.5 g 2 times a day; in more severe cases – up to 0.75 g 2 times a day (if parenteral treatment is not carried out). The course of treatment is usually 5-15 days.

In case of impaired renal function, the usual doses are first given, and then they are reduced taking into account creatinine clearance (the rate of blood purification from the final product of nitrogen metabolism – creatinine).

Treatment should only be prescribed by doctors experienced in treating cystic fibrosis and/or severe infections in children and adolescents.

Total duration of treatment (possibly including initial parenteral treatment with ciprofloxacin). Cystic fibrosis – 20 mg/kg body weight twice daily with a maximum of 750 mg per dose, for 10 to 14 days.